The following VBA example applies bold formatting to the text of the first frame.
Sub Test()
Dim d As Document
Dim s As Shape
Dim s1 As Shape
Dim s2 As Shape
Dim t As Text
Dim strText As String
strText = "This is a test. This is a test. This is a test. " & _
"This is a test. This is a test. This is a test. "
strText = strText & " This is the next part " & strText & strText
Set d = CreateDocument
Set s = d.ActiveLayer.CreateParagraphText(2, 2, 4, 4, strText)
Set s1 = d.ActiveLayer.CreateParagraphText(5, 5, 8, 8)
Set s2 = d.ActiveLayer.CreateParagraphText(8, 8, 10, 10)
Set t = s.Text
' Link the frames together.
t.Frame.LinkTo s1
s1.Text.Frame.LinkTo s2
' Bold the first frame.
t.Frames.First.Range.Bold = True
End Sub